Veja grátis o arquivo ATLAS DE HEMATOLOGIA (McDONALD) enviado para a disciplina de Hematologia Categoria: Aulas – 18 – Atlas de hematologia, – ,-~,. 1r6logo (Ie b pl”imcra t,-dicioll_ _ Prcfacio de b quinta ec:lici6n._ _ Prcf{lcio de ]a pl;mcra edicibn t. “. Title, Atlas de hematología. Authors, George A. McDonald, J. Paul, Bruce Cruickshank. Edition, 5, illustrated, reprint. Publisher, Médica Panamericana,

Author: Yomuro Vujin
Country: Lithuania
Language: English (Spanish)
Genre: Travel
Published (Last): 14 August 2015
Pages: 53
PDF File Size: 11.4 Mb
ePub File Size: 3.67 Mb
ISBN: 936-3-15129-215-6
Downloads: 77731
Price: Free* [*Free Regsitration Required]
Uploader: Nijas

International Agency for Research on Cancer, A search in the PubMed database using terms Gumprecht chronic lymphocytic leukemia revealed just five reports 4, 12, 13, 36, 37what confirms that the term has fallen into disuse. It should be noted that the mechanisms of lymphocyte destruction in CLL and in viral diseases are distinct. Rev Bras Hematol Hemotv. The expression Gumprecht shadows must be used only for cases of CLL, not to describe ruptured lymphocytes present in other situations with lymphocytosis, associated with either viral diseases or other causes.

If you have persistent cookies enabled as well, then we will be able to remember you across browser restarts and computer reboots. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Annales de Biologie Cliniquemcsonald.

Cookies come in two flavours – persistent and transient. A dictionary of medical eponyms.

Most of the times, CLL is unexpectedly diagnosed by a routine blood test. In both cases you should know how to switch cookies back on!


Flow cytometry allows identification of cluster differentiation CD specific to B lymphocytes CD14, CD20, and CD23 and, as a result, characterizes the clonal origin of these lymphocytes Cytogenetics helps to detect abnormalities,especially in chromosomes 11 and The microscopic examination of blood cells is surely an essential step for the diagnosis of Hemato,ogia Cookies are little nuggets of information that web servers store on your computer to make it easier for them to keep track of your browsing session.

It is known that viral conditions present with a high number of circulating lymphocytes, which are also susceptible hematologoa lysis. Subscribe to our newsletter Some error text Name. The World Health Organization WHO describes CLL atllas a neoplasm of small B lymphocytes, with slightly irregular membrane present in peripheral blood, bone marrow, spleen and lymph hrmatologia, along with prolymphocytes and paraimmunoblasts that proliferate in the infiltrated tissues Additional tests may be ordered, such as bone marrow biopsy for exclusion of idiopathic cytopenias; detection of genetic abnormalities, principally of a deletion of chromosomes 17 [del 17p ] and 11 [del 11q ]; flow cytometry to evaluate ZAP and CD38 expression, whose presence indicates poor prognosis; and computed tomography Mcodnald for the staging of the disease Inappropriate use of this term can cause great anxiety in individuals receiving their blood count results, as well as in their families.


Authentication ends after about 15 minutues of inactivity, or when you explicitly choose to end it. Services on Demand Journal. World Health Organization classification of tumours of haematopoietic and lymphoid tissues. A activation email has been sent to you.

CLL is a relatively rare lymphoproliferative disorder. Annals of Oncologyv. It is benign in comparison to other leukemias, shows slow evolution and marked leukocytosis in the blood Sometimes, we also use a cookie to keep track of your trolley contents.

Let’s connect Contact Details Facebook Twitter. Manual de hematologia de Williams. Please click the link in that email to activate your subscription.

Atlas de Hematologia : Bruce Cruickshank :

In a web search engine commonly used to clear doubts on medical terms, there are countless pages where Gumprecht shadows are associated with CLL. Email address subscribed successfully. To access your account information you need to be authenticated, which means that you need to enter your password to confirm that you are indeed the person that the cookie claims you to be. Before begining immunosuppressive therapy, the following is recommended: ESMO clinical practice guidelines for diagnosis, treatment and follow-up.

This doesn’t mean that anyone who uses your computer can access your account information as we separate association what the cookie provides from authentication.

A literature review revealed that this term is restricted to CLL cases, and should not be applied to lymphocytosis-related conditions. Blood Cellsv. Since the presence of viroses may cause the appearance of images similar to those observed in CLL because of lymphocyte lysis, a literature review was undertaken by searching the word Gumprecht referring to images of lymphocyte lysates that occur in viral diseases.


More hemaatologia techniques are required for the proper classification To the nucleolar bodies nucleoli in cells of the lymphocytic lineage in atlaas suffering from B-chronic lymphocytic leukemia. Persistent cookies are stored on your hard disk and have a pre-defined expiry date.

However, a search in a web search engine using the term Gumprecht and lymphocytes revealed innumerable pages where it is associated with CLL.

Since hyperplasia of lymphoid tissues and lymphocytosis may occur in other infectious processes, especially viral diseases, and in chronic inflammatory processes, such as arthritis, lupus erythematosus, vasculitis, sarcoidosis, etc. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: All mainstream modern browsers have cookies enabled by default, so if you’ve been directed to this page it probably means you’re uisng a weird and wonderful browser of your own choosing, or have disabled cookies yourself.

Ann Biol Clinv. The serum levels of immunoglobulins CD20 and CD79b are significantly reduced in comparison to normal B-lineage cells. The expression Gumprecht shadows derived from the German researcher Ferdinand Adolph Gumprecht 42as he observed the blood films of patients with chronic lymphocytic leukemia CLL Figure.

When the expiry date is reached your computer deletes the cookie. Gumprecht; chronic lymphocytic leukemia; viruses. CLL is suspected when the blood film reveals an expressive increase in uniform-appearing lymphocytes and the presence of destroyed lymphocytes.

Besides, serum determination of lactate dehydrogenase LDHbilirubin, immunoglobulins, and antiglobulins composes the test panel currently used to diagnose CLL 6. Relevance of cytological and immunophenotypical analysis for the diagnosis of B-cell chronic lymphocytic leukaemia. The ruptured lymphocytes, stained in pink, show themselves irregular and constitute the Gumprecht shadows